Publications

Project 1 Publications:

  1. Associations between social, biologic, and behavioral factors and biomarkers of oxidative stress during pregnancy: Findings from four ECHO cohorts. Eick SM, Geiger SD, Alshawabkeh A, Aung M, Barrett E, Bush NR, Cordero JF, Ferguson KK, Meeker JD, Milne GL, Nguyen RHN, Padula AM, Sathyanarayana S, Welch BM, Schantz SL, Woodruff TJ, Morello-Frosch R.Sci Total Environ. 2022 Apr 28;:155596.doi: 10.1016/j.scitotenv.2022.155596.[Epub ahead of print]PubMed PMID: 35490822; NIHMSID:NIHMS1803455.
  2. Identification of profiles and determinants of maternal pregnancy urinary biomarkers of phthalates and replacements in the Illinois Kids Development Study. Pacyga DC, Haggerty DK, Nicol M, Henning M, Calafat AM, Braun JM, Schantz SL, Strakovsky RS.Environ Int. 2022 Apr;162:107150.doi: 10.1016/j.envint.2022.107150.Epub 2022 Mar 2.PubMed PMID: 35247685; PubMed Central PMCID: PMC8967784.
  3. Examining the association between prenatal maternal stress and infant non-nutritive suck. Zimmerman E, Aguiar A, Aung MT, Geiger SD, Hines M, Woodbury ML, Martens A, Huerta-Montanez G, Cordero JF, Meeker JD, Schantz SL, Alshawabkeh AN. Pediatr Res. 2021 Dec 16;.doi: 10.1038/s41390-021-01894-9.[Epub ahead of print]PubMed PMID: 34916626; NIHMSID:NIHMS1760895.
  4. Maternal phthalate and phthalate alternative metabolites and urinary biomarkers of estrogens and testosterones across pregnancy. Pacyga DC, Gardiner JC, Flaws JA, Li Z, Calafat AM, Korrick SA, Schantz SL, Strakovsky RS. Environ Int. 2021 Oct;155:106676. doi: 10.1016/j.envint.2021.106676. Epub 2021 Jun 8. PMID: 34116379
  5. Associations of prenatal maternal stress with measures of cognition in 7.5-month-old infants. Merced-Nieves FM, Dzwilewski KLC, Aguiar A, Lin J, Schantz SL. Dev Psychobiol. 2021 Jul;63(5):960-972.doi: 10.1002/dev.22059.Epub 2020 Nov 9.PubMed PMID: 33169388; PubMed Central PMCID: PMC8278565.
  6. Associations of prenatal exposure to phthalates with measures of cognition in 7.5-month-old infants. Dzwilewski KLC, Woodbury ML, Aguiar A, Shoaff J, Merced-Nieves F, Korrick SA, Schantz SL. Neurotoxicology. 2021 May;84:84-95. doi: 10.1016/j.neuro.2021.03.001. Epub 2021 Mar 8. PMID: 33705789
  7. Associations of Prenatal Exposure to Phthalates with Measures of Cognition in 4.5-Month-Old Infants. Merced-Nieves FM, Dzwilewski KLC, Aguiar A, Musaad S, Korrick SA, Schantz SL. Int J Environ Res Public Health. 2021 Feb 13;18(4):1838. doi: 10.3390/ijerph18041838. PMID: 33668677 Free PMC article.
  8. Associations of Maternal Stress, Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFAS), and Demographic Risk Factors with Birth Outcomes and Offspring Neurodevelopment: An Overview of the ECHO.CA.IL Prospective Birth Cohorts. Eick SM, Enright EA, Geiger SD, Dzwilewski KLC, DeMicco E, Smith S, Park JS, Aguiar A, Woodruff TJ, Morello-Frosch R, Schantz SL. Int J Environ Res Public Health. 2021 Jan 16;18(2):742. doi: 10.3390/ijerph18020742. PMID: 33467168 Free PMC article. Review.
  9. Associations of prenatal maternal stress with measures of cognition in 7.5-month-old infants.Merced-Nieves FM, Dzwilewski KLC, Aguiar A, Lin J, Schantz SL. Dev Psychobiol. 2021 Jul;63(5):960-972. doi: 10.1002/dev.22059. Epub 2020 Nov 9. PMID: 33169388 Free PMC article.
  10. Association of Exposure to Endocrine-Disrupting Chemicals During Adolescence With Attention-Deficit/Hyperactivity Disorder-Related Behaviors. Shoaff JR, Coull B, Weuve J, Bellinger DC, Calafat AM, Schantz SL, Korrick SA. JAMA Netw Open. 2020 Aug 3;3(8):e2015041. doi: 10.1001/jamanetworkopen.2020.15041. PMID: 32857150 Free PMC article.
  11. Characterization of performance on an automated visual recognition memory task in 7.5-month-old infants. Dzwilewski KLC, Merced-Nieves FM, Aguiar A, Korrick SA, Schantz SL. Neurotoxicol Teratol. 2020 Sep-Oct;81:106904. doi: 10.1016/j.ntt.2020.106904. Epub 2020 May 30. PMID: 32485220 Free PMC article.
  12. Association of prenatal maternal perceived stress with a sexually dimorphic measure of cognition in 4.5-month-old infants. Merced-Nieves FM, Aguiar A, Dzwilewski KLC, Musaad S, Korrick SA, Schantz SL. Neurotoxicol Teratol. 2020 Jan-Feb;77:106850. doi: 10.1016/j.ntt.2019.106850. Epub 2019 Dec 6. PMID: 31812786 Free PMC article.
  13. Endocrine disrupting chemical exposure and maladaptive behavior during adolescence. Shoaff JR, Calafat AM, Schantz SL, Korrick SA. Environ Res. 2019 May;172:231-241. doi: 10.1016/j.envres.2018.12.053. Epub 2018 Dec 22. PMID: 30818232 Free PMC article.
  14. A possible approach to improving the reproducibility of urinary concentrations of phthalate metabolites and phenols during pregnancy. Yazdy MM, Coull BA, Gardiner JC, Aguiar A, Calafat AM, Xiaoyun Ye, Schantz SL, Korrick SA. J Expo Sci Environ Epidemiol. 2018 Sep;28(5):448-460. doi: 10.1038/s41370-018-0050-0. Epub 2018 Jul 17. PMID: 30018406 Free PMC article.
  15. Impacts of bisphenol A (BPA) and phthalate exposures on epigenetic outcomes in the human placenta. Strakovsky RS, Schantz SL. Environ Epigenet. 2018 Sep 7;4(3):dvy022. doi: 10.1093/eep/dvy022. eCollection 2018 Jul. PMID: 30210810 Free PMC article.
  16. Prenatal chemical exposures and child language development. Dzwilewski KL, Schantz SL. J Commun Disord. 2015 Sep-Oct;57:41-65. doi: 10.1016/j.jcomdis.2015.07.002. Epub 2015 Jul 23. PMID: 26255253 Free PMC article. Review.
  17. Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. Strakovsky RS, Wang H, Engeseth NJ, Flaws JA, Helferich WG, Pan YX, Lezmi S. Toxicol Appl Pharmacol. 2015 Apr 15;284(2):101-12. doi: 10.1016/j.taap.2015.02.021. Epub 2015 Mar 5. PMID: 25748669 Free PMC article.
  18. The influence of obesity on blood mercury levels for U.S. non-pregnant adults and children: NHANES 2007-2010. Rothenberg SE, Korrick SA, Fayad R. Environ Res. 2015 Apr;138:173-80. doi: 10.1016/j.envres.2015.01.018. Epub 2015 Feb 24. PMID: 25721244 Free PMC article.

Project 2 Publications:

  1. Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice. Li K, Liszka M, Zhou C, Brehm E, Flaws JA, Nowak RA. Reprod Toxicol. 2020 Apr;93:178-190. doi: 10.1016/j.reprotox.2020.02.012. Epub 2020 Feb 29. PMID: 32126281
  2. Germline-dependent transmission of male reproductive traits induced by an endocrine disruptor, di-2-ethylhexyl phthalate, in future generations. Barakat R, Lin PC, Park CJ, Zeineldin M, Zhou S, Rattan S, Brehm E, Flaws JA, Ko CJ. Sci Rep. 2020 Mar 31;10(1):5705. doi: 10.1038/s41598-020-62584-w. PMID: 32235866 Free PMC article.
  3. The epigenetic impacts of endocrine disruptors on female reproduction across generations†. Rattan S, Flaws JA. Biol Reprod. 2019 Sep 1;101(3):635-644. doi: 10.1093/biolre/ioz081. PMID: 31077281 Free PMC article. Review.
  4. Prenatal and ancestral exposure to di(2-ethylhexyl) phthalate alters gene expression and DNA methylation in mouse ovaries. Rattan S, Beers HK, Kannan A, Ramakrishnan A, Brehm E, Bagchi I, Irudayaraj JMK, Flaws JA. Toxicol Appl Pharmacol. 2019 Sep 15;379:114629. doi: 10.1016/j.taap.2019.114629. Epub 2019 Jun 15. PMID: 31211961 Free PMC article.
  5. Transgenerational Bisphenol A Causes Deficits in Social Recognition and Alters Postsynaptic Density Genes in Mice. Wolstenholme JT, Drobná Z, Henriksen AD, Goldsby JA, Stevenson R, Irvin JW, Flaws JA, Rissman EF. Endocrinology. 2019 Aug 1;160(8):1854-1867. doi: 10.1210/en.2019-00196. PMID: 31188430 Free PMC article.
  6. Exposure to di-(2-ethylhexyl) phthalate transgenerationally alters anxiety-like behavior and amygdala gene expression in adult male and female mice. Hatcher KM, Willing J, Chiang C, Rattan S, Flaws JA, Mahoney MM. Physiol Behav. 2019 Aug 1;207:7-14. doi: 10.1016/j.physbeh.2019.04.018. Epub 2019 Apr 22. PMID: 31022410 Free PMC article.
  7. Transgenerational Effects of Endocrine-Disrupting Chemicals on Male and Female Reproduction. Brehm E, Flaws JA. Endocrinology. 2019 Jun 1;160(6):1421-1435. doi: 10.1210/en.2019-00034. PMID: 30998239 Free PMC article. Review.
  8. Sanitary pads and diapers contain higher phthalate contents than those in common commercial plastic products. Park CJ, Barakat R, Ulanov A, Li Z, Lin PC, Chiu K, Zhou S, Perez P, Lee J, Flaws J, Ko CJ. Reprod Toxicol. 2019 Mar;84:114-121. doi: 10.1016/j.reprotox.2019.01.005. Epub 2019 Jan 16. PMID: 30659930 Free PMC article.
  9. Prenatal Exposure to DEHP Induces Neuronal Degeneration and Neurobehavioral Abnormalities in Adult Male Mice. Barakat R, Lin PC, Park CJ, Best-Popescu C, Bakry HH, Abosalem ME, Abdelaleem NM, Flaws JA, Ko C. Toxicol Sci. 2018 Aug 1;164(2):439-452. doi: 10.1093/toxsci/kfy103. PMID: 29688563 Free PMC article.
  10. Di(2-Ethylhexyl) Phthalate Exposure During Prenatal Development Causes Adverse Transgenerational Effects on Female Fertility in Mice. Rattan S, Brehm E, Gao L, Flaws JA. Toxicol Sci. 2018 Jun 1;163(2):420-429. doi: 10.1093/toxsci/kfy042. PMID: 29471507 Free PMC article.
  11. Bisphenol A and Phthalates Modulate Peritoneal Macrophage Function in Female Mice Involving SYMD2-H3K36 Dimethylation. Li Q, Lawrence CR, Nowak RA, Flaws JA, Bagchi MK, Bagchi IC. Endocrinology. 2018 May 1;159(5):2216-2228. doi: 10.1210/en.2017-03000. PMID: 29718165 Free PMC article.
  12. Prenatal Exposure to Di(2-Ethylhexyl) Phthalate Causes Long-Term Transgenerational Effects on Female Reproduction in Mice.Brehm E, Rattan S, Gao L, Flaws JA. Endocrinology. 2018 Feb 1;159(2):795-809. doi: 10.1210/en.2017-03004. PMID: 29228129 Free PMC article.
  13. Effects of Exposure to the Endocrine-Disrupting Chemical Bisphenol A During Critical Windows of Murine Pituitary Development. Eckstrum KS, Edwards W, Banerjee A, Wang W, Flaws JA, Katzenellenbogen JA, Kim SH, Raetzman LT. Endocrinology. 2018 Jan 1;159(1):119-131. doi: 10.1210/en.2017-00565. PMID: 29092056 Free PMC article.
  14. Prenatal exposure to di(2-ethylhexyl) phthalate disrupts ovarian function in a transgenerational manner in female mice. Rattan S, Brehm E, Gao L, Niermann S, Flaws JA. Biol Reprod. 2018 Jan 1;98(1):130-145. doi: 10.1093/biolre/iox154. PMID: 29165555 Free PMC article.
  15. Transgenerational Effects of Bisphenol A on Gene Expression and DNA Methylation of Imprinted Genes in Brain. Drobná Z, Henriksen AD, Wolstenholme JT, Montiel C, Lambeth PS, Shang S, Harris EP, Zhou C, Flaws JA, Adli M, Rissman EF. Endocrinology. 2018 Jan 1;159(1):132-144. doi: 10.1210/en.2017-00730. PMID: 29165653 Free PMC article.
  16. The effects of in utero bisphenol A exposure on ovarian follicle numbers and steroidogenesis in the F1 and F2 generations of mice. Mahalingam S, Ther L, Gao L, Wang W, Ziv-Gal A, Flaws JA. Reprod Toxicol. 2017 Dec;74:150-157. doi: 10.1016/j.reprotox.2017.09.013. Epub 2017 Sep 29. PMID: 28970132 Free PMC article.
  17. Bisphenol A impairs decidualization of human uterine stromal fibroblasts. Olson MR, Su R, Flaws JA, Fazleabas AT. Reprod Toxicol. 2017 Oct;73:339-344. doi: 10.1016/j.reprotox.2017.07.008. Epub 2017 Jul 17. PMID: 28729173 Free PMC article.
  18. Exposure to an Environmentally Relevant Phthalate Mixture Causes Transgenerational Effects on Female Reproduction in Mice. Zhou C, Gao L, Flaws JA. Endocrinology. 2017 Jun 1;158(6):1739-1754. doi: 10.1210/en.2017-00100. PMID: 28368545 Free PMC article.
  19. Prenatal Exposure to DEHP Induces Premature Reproductive Senescence in Male Mice. Barakat R, Lin PP, Rattan S, Brehm E, Canisso IF, Abosalum ME, Flaws JA, Hess R, Ko C. Toxicol Sci. 2017 Mar 1;156(1):96-108. doi: 10.1093/toxsci/kfw248. PMID: 28082598 Free PMC article.
  20. Effects of an Environmentally Relevant Phthalate Mixture on Cultured Mouse Antral Follicles. Zhou C, Flaws JA. Toxicol Sci. 2017 Mar 1;156(1):217-229. doi: 10.1093/toxsci/kfw245. PMID: 28013214 Free PMC article.
  21. Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice. Zhou C, Gao L, Flaws JA. Toxicol Appl Pharmacol. 2017 Mar 1;318:49-57. doi: 10.1016/j.taap.2017.01.010. Epub 2017 Jan 23. PMID: 28126412 Free PMC article.
  22. Evidence for bisphenol A-induced female infertility: a review (2007-2016). Ziv-Gal A, Flaws JA. Fertil Steril. 2016 Sep 15;106(4):827-56. doi: 10.1016/j.fertnstert.2016.06.027. Epub 2016 Jul 12. PMID: 27417731 Free PMC article. Review.
  23. Chronic Exposure to Bisphenol A Affects Uterine Function During Early Pregnancy in Mice. Li Q, Davila J, Kannan A, Flaws JA, Bagchi MK, Bagchi IC. Endocrinology. 2016 May;157(5):1764-74. doi: 10.1210/en.2015-2031. Epub 2016 Mar 29. PMID: 27022677 Free PMC article.
  24. The effects of in utero bisphenol A exposure on the ovaries in multiple generations of mice. Berger A, Ziv-Gal A, Cudiamat J, Wang W, Zhou C, Flaws JA. Reprod Toxicol. 2016 Apr;60:39-52. doi: 10.1016/j.reprotox.2015.12.004. Epub 2015 Dec 30. PMID: 26746108 Free PMC article.
  25. In utero growth restriction and catch-up adipogenesis after developmental di (2-ethylhexyl) phthalate exposure cause glucose intolerance in adult male rats following a high-fat dietary challenge. Strakovsky RS, Lezmi S, Shkoda I, Flaws JA, Helferich WG, Pan YX. J Nutr Biochem. 2015 Nov;26(11):1208-20. doi: 10.1016/j.jnutbio.2015.05.012. Epub 2015 Jun 20. PMID: 26188368 Free PMC article.
  26. Bisphenol A exposure inhibits germ cell nest breakdown by reducing apoptosis in cultured neonatal mouse ovaries. Zhou C, Wang W, Peretz J, Flaws JA. Reprod Toxicol. 2015 Nov;57:87-99. doi: 10.1016/j.reprotox.2015.05.012. Epub 2015 Jun 4. PMID: 26049153 Free PMC article.
  27. The effects of in utero bisphenol A exposure on reproductive capacity in several generations of mice. Ziv-Gal A, Wang W, Zhou C, Flaws JA. Toxicol Appl Pharmacol. 2015 May 1;284(3):354-62. doi: 10.1016/j.taap.2015.03.003. Epub 2015 Mar 11. PMID: 25771130 Free PMC article.
  28. Prenatal exposure to di-(2-ethylhexyl) phthalate (DEHP) affects reproductive outcomes in female mice. Niermann S, Rattan S, Brehm E, Flaws JA. Reprod Toxicol. 2015 Jun;53:23-32. doi: 10.1016/j.reprotox.2015.02.013. Epub 2015 Mar 9. PMID: 25765777 Free PMC article.
  29. The effects of in utero bisphenol A exposure on reproductive capacity in several generations of mice. Ziv-Gal A, Wang W, Zhou C, Flaws JA. Toxicol Appl Pharmacol. 2015 May 1;284(3):354-62. doi: 10.1016/j.taap.2015.03.003. Epub 2015 Mar 11. PMID: 25771130 Free PMC article.
  30. Bisphenol a and reproductive health: update of experimental and human evidence, 2007-2013. Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA. Environ Health Perspect. 2014 Aug;122(8):775-86. doi: 10.1289/ehp.1307728. Epub 2014 Jun 4. PMID: 24896072 Free PMC article. Review.
  31. In utero bisphenol A exposure disrupts germ cell nest breakdown and reduces fertility with age in the mouse. Wang W, Hafner KS, Flaws JA. Toxicol Appl Pharmacol. 2014 Apr 15;276(2):157-64. doi: 10.1016/j.taap.2014.02.009. Epub 2014 Feb 25. PMID: 24576723 Free PMC article.
  32. Mouse strain does not influence the overall effects of bisphenol a-induced toxicity in adult antral follicles. Peretz J, Neese SL, Flaws JA. Biol Reprod. 2013 Nov 7;89(5):108. doi: 10.1095/biolreprod.113.111864. Print 2013 Nov. PMID: 24025742 Free PMC article.

Project 3 Publications:

  1. Perinatal phthalate exposure increases developmental apoptosis in the rat medial prefrontal cortex. Sellinger EP, Riesgo VR, Brinks AS, Willing J, Juraska JM. Neurotoxicology. 2021 Dec;87:167-173. doi: 10.1016/j.neuro.2021.09.007. Epub 2021 Sep 29. PMID: 34599995
  2. Adolescent stress during, but not after, pubertal onset impairs indices of prepulse inhibition in adult rats. Drzewiecki CM, Willing J, Cortes LR, Juraska JM. Dev Psychobiol. 2021 Jul;63(5):837-850. doi: 10.1002/dev.22111. Epub 2021 Feb 24. PMID: 33629385
  3. Influences of age and pubertal status on number and intensity of perineuronal nets in the rat medial prefrontal cortex. Drzewiecki CM, Willing J, Juraska JM. Brain Struct Funct. 2020 Nov;225(8):2495-2507. doi: 10.1007/s00429-020-02137-z. Epub 2020 Sep 10. PMID: 32914251 Free PMC article.
  4. Behavioral effects in adult rats exposed to low doses of a phthalate mixture during the perinatal or adolescent period. Sellinger EP, Kougias DG, Drzewiecki CM, Juraska JM. Neurotoxicol Teratol. 2020 May-Jun;79:106886. doi: 10.1016/j.ntt.2020.106886. Epub 2020 Apr 18. PMID: 32315766 Free PMC article.
  5. Perinatal High-Fat Diet and Bisphenol A: Effects on Behavior and Gene Expression in the Medial Prefrontal Cortex. Wise LM, Hernández-Saavedra D, Boas SM, Pan YX, Juraska JM. Dev Neurosci. 2019;41(1-2):1-16. doi: 10.1159/000494879. Epub 2018 Dec 21. PMID: 30580332 Free PMC article.
  6. Perinatal Exposure to an Environmentally Relevant Mixture of Phthalates Results in a Lower Number of Neurons and Synapses in the Medial Prefrontal Cortex and Decreased Cognitive Flexibility in Adult Male and Female Rats. Kougias DG, Sellinger EP, Willing J, Juraska JM. J Neurosci. 2018 Aug 1;38(31):6864-6872. doi: 10.1523/JNEUROSCI.0607-18.2018. Epub 2018 Jul 16. PMID: 30012688 Free PMC article.
  7. Effects of Perinatal Exposure to Phthalates and a High-Fat Diet on Maternal Behavior and Pup Development and Social Play. Kougias DG, Cortes LR, Moody L, Rhoads S, Pan YX, Juraska JM. Endocrinology. 2018 Feb 1;159(2):1088-1105. doi: 10.1210/en.2017-03047. PMID: 29300916 Free PMC article.
  8. Long-term effects of adolescent exposure to bisphenol A on neuron and glia number in the rat prefrontal cortex: Differences between the sexes and cell type. Wise LM, Sadowski RN, Kim T, Willing J, Juraska JM. Neurotoxicology. 2016 Mar;53:186-192. doi: 10.1016/j.neuro.2016.01.011. Epub 2016 Jan 29. PMID: 26828634 Free PMC article.